For a mastectomy in Houston, Texas, MD Anderson Cancer Center is widely regarded as one of the best options, offering specialized breast cancer care with a highly experienced surgical team. Known for its advanced techniques and cutting-edge treatments, MD Anderson provides personalized care tailored to each patient’s needs. Houston Methodist Hospital is another excellent choice, known for its comprehensive approach to breast cancer, including minimally invasive mastectomy procedures and exceptional post-operative care. Additionally, Baylor St. Luke's Medical Center offers a well-established breast cancer program with a focus on patient-centered care and optimal cosmetic outcomes following surgery. These hospitals provide top-tier care for mastectomy procedures, ensuring that patients receive the best possible treatment and support throughout their recovery.