The hospital's history goes back to 1909, when nuns first arrived in the garrison city, opening St Catherine's Hospital behind the St. Ann's Presentation Convent High School, Rawalpindi. Anna Maria Dengel, an Austrian nun, worked here for many years and eventually founded the Medical Mission Sisters in the United States in 1925.

Holy Family Hospital in Rawalpindi offers a wide range of medical specialities, including General Medicine, General Surgery, Cardiology, Orthopaedics, Paediatrics, Obstetrics and Gynaecology, Ophthalmology, Dermatology, Neurology, and Psychiatry. They also have specialists in Hematology, ENT (Ear, Nose, & Throat), Gastroenterology, Neurosurgery, Oncology, Urology, Plastic Surgery, and Family Medicine. 

Holy Family Hospital boasts a modern infrastructure equipped to handle the demands of a high-volume patient load. The facility is designed to provide comprehensive care across a wide spectrum of medical needs.

Holy Family Hospital Rawalpindi's mission is to provide compassionate and comprehensive healthcare, with a focus on quality care and affordable services for all, regardless of background. Their vision is to be a leading healthcare institution that continues to improve the lives of patients and the community through excellent medical care and education.