The Aga Khan University Hospital (AKUH) is a not-for-profit academic medical center that provides comprehensive clinical services under one roof. In addition to its quaternary care hospital in Karachi, AKUH Health System operates a network of four off-campus secondary care hospitals, 19 medical centers, and over 300 clinical laboratories in Pakistan. The system also includes 50+ pharmacies across 130 cities in Pakistan. AKUH extends its care beyond hospital walls with Home Healthcare Services. Generous welfare and zakat programs are available to assist patients in financial need.

Recognised for its commitment to quality care and patient safety, AKUH is accredited by the Joint Commission International (JCI), a global gold standard in healthcare. Its Clinical Laboratories are also accredited by the College of American Pathologists (CAP), further underscoring AKUH's commitment to excellence. In October 2024, the Aga Khan University Hospital, Pakistan, was honored with the 'Best Hospital of the Year' award, presented by the President of Pakistan at the FPCCI Achievement Awards.

 The Aga Khan Maternal and Child Care Centre (AKMCCC) in Hyderabad specializes in comprehensive healthcare services for women and children, along with a range of general and specialized medical treatments. The hospital excels in Obstetrics & Gynecology, Pediatrics, Pediatric Surgery, and Neonatal Care. Additionally, AKMCCC offers specialized services in Cardiology, Dermatology, ENT (Ear, Nose, and Throat), Internal Medicine, and General Surgery. The hospital also provides Orthopedic Surgery, Urology, Dental Services, Anesthesiology, Physiotherapy, and Nutrition & Dietetics, ensuring holistic patient care.

AKMCCC is committed to providing high-quality healthcare services, as evidenced by its ISO 9001-2015 certification. The hospital offers 24/7 urgent care services for women and children, fully equipped modern delivery rooms, inpatient and outpatient departments, advanced diagnostic and laboratory services, and a well-stocked pharmacy. Additionally, AKMCCC provides video consultation services, enhancing accessibility for patients and reducing the need for travel.

• ​​​Strive for excellence in healthcare through the provision of the highest quality, expert, compassionate and ethical care to all patients irrespective of their background. 
• Develop, implement and evaluate innovations in health care, research and education so as to improve the quality of people's health.
• Support the teaching, research and service missions of the University through an enabling and collaborative environment that motivates and inspires excellence.
• Provide access for financially disadvantaged patients who may not, on account of financial difficulties, be able to afford to pay for their care, and to reach out to those who might not otherwise present themselves at the Hospital.
• Contribute to the development of a system of health care encompassing primary, secondary and tertiary care, and not geographically confined to the Main Hospital Campus facility.
• Develop new services in response to public expectations on an economically viable and sustainable basis.
• Implement strategies that demonstrate the ability of the institution to be self-sustaining in, and supportive of, health systems-strengthening for the nation, and the region, that it serves, and developing nation environment.​​